Page 14 Electrochemical strips to manage cancer in decentralized settings Pro Stefano Cinti Department of Pharmacy, University of Naples Federico II Via D. Montesano 49, 80131 Naples stefano.cinti@unina.it Point-of-care testing (PoC) is revolutionizing the healthcare sector improving patient care in daily hospital practice and allowing reaching even remote areas. In the frame of cancer management, the design and validation of PoC enabling the non-invasive, rapid detection of cancer markers is urgently required to implement liquid biopsy. However, despite substantial advances in sensing technologies, the development, preparation, and use of self-testing devices is still confined to specialist laboratories and users. Decentralized analytical devices will enormously impact daily lives, enabling people to analyze diverse clinical, environmental, and food samples, evaluate them and make predictions to improve quality of life, particularly in remote, resource-scarce areas. In recent years, paper-based analytical tools have attracted a great deal of attention; the well-known properties of paper, such as abundance, affordability, lightness, and biodegradability, combined with features of printed electrochemical sensors, have enabled the development of sustainable devices that drive (bio)sensors beyond the state of the art.A wide overview regarding application ranging from DNA to miRNA detection will be provided, with the aim in showing the potentialities of portable electrochemical biosensors for improving society involvement in monitoring circulating nucleic acids (and not only) associated to cancer. Stefano Cinti is an Associate Professor at the Department of Pharmacy, University of Naples “Federico II”. He obtained a Ph.D. in Chemical Sciences in 2016 in the group headed by Prof. Giuseppe Palleschi at the University of Rome “Tor Vergata”. He leads the uninanobiosensors Lab (uninanobiosensors.com) at University of Naples “Federico II”, and his research interests include the development of electrochemical sensors, portable diagnostics, paper-based devices and nanomaterials. During his research activity, he had the opportunity to spend a period abroad in Finland, U.K., U.S., Germany, and Spain. He has published more than 80 papers in peer-reviewed journals, with an H-index of 35 and > 4000 citations.Among all the prizes and certificates, in 2022 he was awarded with the early career award from International Society of Electrochemistry in Analytical Electrochemistry, in 2022 he was awarded with Biosensors 2022 Young Investigator Award, in 2023 he was awarded a Sensor Division Early Career Award by ECS and in 2022 he has been recognized as the World’s Top 2% Scientists. He is the coordinator of the Chemical Cultural Diffusion group of Italian Chemical Society. He is the Chair of AMYC-BIOMED, a multidisciplinary conference for young chemists in the biomedical sciences. He is very active in communicating science to nonspecialized audience through TV shows, radio, and magazine.
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