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Sensor100

May 2016

New approach to sorting cells

Microfluidic device distinguishes cells based on how they respond

to acoustic vibrations.

A team of MIT researchers has now developed

a new way to sort cells, based on their acoustic

properties — that is, how they are affected by

sound waves, which depends on how dense

and compressible the cells are. The new device

consists of a microfluidic channel that vibrates

at a very low frequency.As cells flow through

the channel, they are pushed to a certain posi-

tion depending on how they interact with the

acoustic forces generated by the vibration.

Using this approach, the researchers found that they could distinguish three different

types of white blood cells — monocytes, lymphocytes, and neutrophils — even though

monocytes and neutrophils are very similar in size. In addition to analyzing red and

white blood cells, this technology could also be used for isolating tumor cells from a

patient’s blood sample, perhaps to monitor the progression of cancer.The researchers

also showed in this study that they can distinguish different types of tumor cells based

on their acoustic properties.

MIT News

May 16

TheTheranos Story Continues

Blood-testing firmTheranos has voided two years’ worth of results obtained using its

Edison platform and has sent tens of thousands of corrected reports to doctors and

patients, theWall Street Journal reports.

COO Sunny Balwani has resigned from the company.

Reported by

GenomeWeb

19 May